Gastrointestinal Motility, Part 1: Esophageal Transit and Gastric Emptying

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Gastrointestinal Motility, Part 1: Esophageal Transit and Gastric Emptying.

Although not as well standardized as gastric emptying (GE) scintigraphy, esophageal transit scintigraphy, if performed in a comprehensive manner including both quantitative and qualitative analysis of single- and multiple-swallow studies, is clinically useful when expertise in esophageal manometry is not available or not tolerated and when esophageal manometry or barium videofluoroscopy results...

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Gastrointestinal Motility, Part 2: Small-Bowel and Colon Transit.

Because of the difficulty often encountered in deciding whether a patient's symptoms originate in the upper or lower gastrointestinal tract, gastrointestinal transit scintigraphy is a uniquely suited noninvasive, quantitative, and physiologic method of determining whether there is a motility disorder affecting the stomach, small bowel, or colon. Small-bowel and colon transit studies can be perf...

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Effects of nalbuphine, pentazocine and U50488H on gastric emptying and gastrointestinal transit in the rat.

We studied the effect of mixed agonist-antagonist opioids (nalbuphine and pentazocine) and a kappa opioid agonist (U50488H) on gastric emptying and gastrointestinal transit, and their interactions with morphine in rats. In each group, nalbuphine (0.01-30 mg kg-1), pentazocine (1-30 mg kg-1), U50488H (1-100 mg kg(-1)1) or saline was injected i.p. at 0 min. Another four groups of rats received mo...

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Differential effects of clonidine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.

We have studied the effect of clonidine, dexmedetomidine and morphine on gastric emptying and gastrointestinal transit in the rat. In one group, each agonist was injected i.p. in 6-12 male Wistar rats. In another group of rats, yohimbine, naloxone or saline was injected with an agonist. At 30 min, radiolabelled saline 1 ml was infused into the stomach. At 1 h, gastric emptying and gastrointesti...

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Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of liquids in awake rats.

CONTEXT Methotrexate and other anticancer agents can induce intestinal mucositis, which is one of the most common limiting factor that prevent further dose escalation of the methotrexate. OBJECTIVES To evaluate the gastric emptying and gastrointestinal transit of liquids in methotrexate-induced intestinal mucositis. METHODS Wistar rats received methotrexate (2.5 mg/kg/day for 3 days, subcut...

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ژورنال

عنوان ژورنال: Journal of Nuclear Medicine Technology

سال: 2016

ISSN: 0091-4916,1535-5675

DOI: 10.2967/jnumed.112.114314